Web1 day ago · Cocaine has an overwhelming effect on the healthcare system because of its neurologic, gastrointestinal, renal, and endocrine complications; however, its cardiovascular effects are the most common [1]. The effects of cocaine use place a substantial economic and social burden on the healthcare system. Approximately 5 to WebThe fundamental effects of cocaine on cardiovascular system are similar to those observed following an intense, sympathetic stimulation. Cocaine intake results in marked increase in blood pressure, myocardial oxygen demand and heart rate. Coronary blood flow, which increases in response to exercise (endogenous sympathetic stimulation) however ...
Toxin-induced cardiomyopathy: A review and pooled analysis of …
WebAug 15, 2024 · Cocaine is an ester anesthetic used topically to numb the mucous membranes of the oral, nasal, and laryngeal cavities during procedures or surgeries in or through the nasal cavities. Common side effects from systemic absorption of cocaine include high blood pressure (hypertension), rapid heart rate (tachycardia), sinus … WebOct 26, 2024 · Cocaine has many serious medical consequences including cardiac arrhythmias, coronary artery spasm and myocardial infarction, cerebrovascular accidents, subarachnoid hemorrhage, seizures, … mini brake discs and pads
The effects of acute and chronic cocaine use on the heart
WebDec 14, 2016 · Cocaine is an amphipathic molecule that can cross the blood–brain barrier and placenta and increase peripheral and central nervous system (CNS) levels of catecholamines such as norepinephrine, epinephrine, and dopamine. 4 This primarily occurs via blockade of plasmalemmal monoamine transporters involved in reuptake. 17 … WebAsides from the myocardium, cocaine can also increase the risk of ischemic stroke. Cocaine can also cause seizures by lowering the threshold for seizure initiation. Chronic … WebCocaine has also been shown to cause cardiomyopathy and myocarditis. Various mechanisms are responsible for these changes, such as myocardial ischemia, direct toxic effect of cocaine causing myocardial necrosis, tachycardia-induced cardiomyopathy, and autoimmune reaction to cocaine and levamisole (used as a cutting agent with cocaine). 5 most famous motown artists