Irf7 molecular weight
WebPartial IRF7 recombinant protein (127-503 a.a.) Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) ... 503 amino acids, predicted molecular weight of 54 kD, contains an IRF tryptophan pentad repeat responsible for DNA binding Distribution Shuttles between the cytoplasm and nucleus; activated ... WebOct 15, 2012 · Wuhan University, Wuhan, China; 3National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ... IRF7 knockout mice displayed decreased weight gain and adiposity on a HFD. A: the comparison of body weight gains in WT or irf7 / (KO) …
Irf7 molecular weight
Did you know?
WebIRF3 is a member of the interferon regulatory transcription factor (IRF) family. [5] IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized … WebIRF7-mediated control of the Gbp2 gene required the presence and basal activity of the S/T kinase TANK-binding kinase 1 (TBK1), whereas the binding of IRF7 to the Gbp2 promoter …
WebIRF7. IRF7 was originally cloned as a factor that bound to a promoter region in the Epstein-Barr virus using a yeast one-hybrid system (Zhang and Pagano, 1997 ). IRF7, once induced, is present in the cytoplasm as an inactive protein that is also phosphorylated on specific C-terminal residues by TBK1 and/or possibly IKKε kinases ( Fitzgerald et ... WebKnow comprehensive IRF7 protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction. U.S.A. English. Chinese( …
WebMar 7, 2024 · Therefore, although a link between IRF7 and TGIF1 has been observed and the IRF7-TGIF1 axis has been implicated, the molecular mechanism requires further investigation. WebJan 25, 2016 · IRF7 is a putative molecular driver of HBE responses to HRV. Differentially expressed genes were identified in HRV-induced HBE cells (Fig. 2 ), and then the wiring diagram of the IRF7 gene network was reconstructed from these data employing experimentally supported findings from published studies.
WebThe IRF7 lentiviruses transfected HMs expressed IRF7 protein by western blotting (IRF7 molecular weight 58kDa) (Fig 1 E). We successfully constructed lentiviruses vector of IRF7 overexpression. Influence of HM/IRF-7 on GBM (U87-MG) growth and survival in co-culture
WebMay 1, 2008 · IRF7 is an IFN-inducible transcription factor necessary for IFN-stimulated gene (ISG) induction by IFNs ( 29, 31, 32 ). When activated by phosphorylation, IRF7 translocates from the cytoplasm to the nucleus to induce target gene expression by binding to promoter regulatory elements ( 33, 34 ). the play goes wrongWebNov 30, 2024 · The molecular basis underlying stress hematopoiesis remains to be fully understood. In this study, we reported that IRF7 represents an important regulator of stress hematopoiesis. Interferon regulatory factor 7 (IRF7) was dispensable for normal hematopoiesis, whereas its deficiency significantly enhanced hematopoietic stem and … side post battery chargerWebJan 1, 2024 · Aims: Although interferon regulatory factor 7 (IRF7) has known roles in regulating the inflammatory response, vascular smooth muscle cell proliferation, and apoptosis, its role in the pathogenesis of pulmonary hypertension (PH) is unclear. the playground bookWeb503 amino acids, predicted molecular weight of 54 kD, contains an IRF tryptophan pentad repeat responsible for DNA binding Distribution Shuttles between the cytoplasm and nucleus; activated (phosphorylated) form of IRF-7 accumulates in the nucleus Function the play goes wrong londonWebMar 21, 2024 · IRF7 (Interferon Regulatory Factor 7) is a Protein Coding gene. Diseases associated with IRF7 include Immunodeficiency 39 and Predisposition To Severe Viral … side position urban dictionaryWebIRF-7 plays an essential role in the induction of type I interferon in response viral infection (6-8). Like IRF-3, IRF-7 is regulated at multiple serine phosphorylation sites near its … the playground basketball oshawaWebThe ORF encoded 423 amino acids with a molecular weight of 49.426 KDa and a theoretical isoelectric point of 5.71. The putative ScIRF7 protein possesses typical domains of IRF … side pork slow cooker