WebLovastatin, pravastatin and simvastatin are derived from fungal metabolites and have elimination half-lives of 1-3 h. Atorvastatin, cerivastatin (withdrawn from clinical use in 2001), fluvastatin, pitavastatin and rosuvastatin are fully synthetic compounds, with elimination half-lives ranging from 1 h for fluvastatin to 19 h for rosuvastatin. WebSep 4, 2012 · The results showed that the relative risk rates were consistently higher for rosuvastatin than for the other statins. Compared with rosuvastatin, the risk of muscle-related adverse effects was 74% as high for fluvastatin, 55% as high for atorvastatin, 26% as high for simvastatin, 17% as high for pravastatin, and 7.5% as high for lovastatin.
Considerations in the Approach to Appropriate Statin Selection
WebDec 15, 2024 · 10/40. 10/80. * 2013 ACC/AHA guidelines: high-intensity statin lowers cholesterol by >50%, moderate-intensity statin lowers cholesterol by 30-50%, low … WebNov 18, 2024 · The empirical formula for pitavastatin is C 50 H 46 CaF 2 N 2 O 8 and the molecular weight is 880.98. Pitavastatin is odorless and occurs as white to pale-yellow powder. It is freely soluble in pyridine, chloroform, dilute hydrochloric acid, and tetrahydrofuran, soluble in ethylene glycol, sparingly soluble in octanol, slightly soluble in … cooling off externe rotation
Lovastatin vs. Simvastatin; Differences in Side Effects & Dosage
WebApr 9, 2024 · Pitavastatin is well tolerated. The post-marketing LIVES study analyzed safety in 19 925 patients receiving pitavastatin in clinical practice. [10] During a 2-year follow-up, 10.4% of patients ... WebPitavastatin has an average rating of 5.4 out of 10 from a total of 89 ratings on Drugs.com. 41% of reviewers reported a positive effect, while 36% reported a negative effect. Rosuvastatin has an average rating of 5.1 out of 10 from a total of 237 ratings on Drugs.com. 36% of reviewers reported a positive effect, while 46% reported a negative ... WebDec 1, 2024 · Pitavastatin is available in tablets of 1, 2 and 4 mg under the trade names Livalo and Zypitamag. Pitavastatin is one of the more potent statins and is typically used in a comparably lower dose. The … family resorts us